PSEN1-IN-2

SKU: orb2277768

Description

PSEN1-IN-2 (Compound 13K) is a highly potent, selective inhibitor of γ-secretase, specifically targeting both PSEN1-APH1A and PSEN1-APH1B complexes with IC50 values of 6.9 nM and 2.4 nM, respectively. This small molecule is a valuable chemical tool for Alzheimer's disease research, enabling mechanistic studies of amyloid precursor protein processing in cellular and biochemical assays.

Research Area

Cell Biology, Neuroscience, Protein Biochemistry, Stem Cell & Developmental Biology

Key Properties

• MW: 420.88
• Formula: C₂₀H₁₈ClFN₂O₃S
• Target: Gamma-secretase,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Gamma-secretase,Others