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PS1097

SKU: orb3210293

Description

PS1097 is a broad-spectrum antiviral inhibitor with an IC50 of 0.64 μM for BVDV RdRp. It selectively reduces RTN3 protein levels, partially decreases RTN3 mRNA, and does not affect other endoplasmic reticulum-resident proteins. PS1097 inhibits the replication of pestiviruses and various viruses that use the endoplasmic reticulum as a replication hub. It inhibits the enzymatic activity of BVDV RdRp and is active against bovine viral diarrhea virus. PS1097 is applicable in research related to infections by Zika virus, Usutu virus, West Nile virus, COVID-19, coxsackievirus B5, chikungunya virus, and vaccinia virus.

Images & Validation

Key Properties

CAS Number1822320-58-0
MW313.76
FormulaC15H8ClN3OS
SMILESO=C1NC=2C=C3C=CC=NC3=C(Cl)C2N=C1C=4SC=CC4
TargetSARS-CoV,Virus Protease,Anti-infection

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information