Prulifloxacin

SKU: orb1301827

Description

Prulifloxacin (NM441) is a broad-spectrum fluoroquinolone antibiotic that acts by inhibiting bacterial DNA topoisomerase II and IV, thereby blocking DNA replication. It is used in research for studying antibacterial mechanisms and efficacy in both in vitro and in vivo models against various Gram-negative and Gram-positive pathogens.

Research Area

Infectious Disease & Virology, Molecular Biology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 123447-62-1
• MW: 461.46
• Purity: 99.56% (May vary between batches)
• Formula: C₂₁H₂₀FN₃O₆S
• SMILES: CC1Sc2c(C(O)=O)c(=O)c3cc(F)c(cc3n12)N1CCN(Cc2oc(=O)oc2C)CC1
• Target: Antibacterial,Topoisomerase,Antibiotic
• Solubility: H2O:Insoluble;DMSO:2.31 mg/mL (5.01 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.17 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Antibiotic, Bacterial, AF3012, AF-3012, AF 3012, negative, NM 441, NM394, NM441, NM-441, orally, inhibit, Inhibitor, Gram-positive, Topo II, Topo IV, Prulifloxacin, Pruvel, Ulifloxacin

Compound Identifiers

PubChem CID

65947