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Protein kinase inhibitor 5

SKU: orb1944333

Description

Protein kinase inhibitor 5 is a potent and selective TRK-A inhibitor with an IC50 of 1.8 nM. It effectively reduces cell viability in vitro and is a valuable chemical tool for studying NTRK-driven cancers in cellular and biochemical assays.

Research Area

Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

CAS Number2278204-94-5
MW531.6
FormulaC29H31F2N7O
SMILESFC1=C([C@@H]2N(CCC2)C3=NC4=C(NC(=O)C5=CC=C(CN6CCN(C)CC6)C=C5)C=NN4C=C3)C=C(F)C=C1
TargetTrk receptor

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Quality Guarantee

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Key Properties

No computed properties available.

Protocol Information