Protein Kinase C β Peptide

SKU: orb1981022

Description

This peptide fragment of Protein Kinase Cβ (PKCβ) is linked to reduced nitric oxide production in endothelial cells during hyperglycemia. Its inhibition protects against acute hyperglycemia-induced endothelial dysfunction, making it a valuable research tool for studying vascular complications in diabetes through in vitro and in vivo models.

Research Area

Epigenetics & Chromatin, Signal Transduction

Key Properties

• Target: PKC
• CAS Number: 309247-50-5
• MW: 1966.18
• Formula: C₈₄H₁₃₆N₂₂O₃₀S
• SMILES: C([C@@H](NC([C@@H](NC(=O)[C@H]1N(C(CN)=O)CCC1)CCCCN)=O)[C@@H](C)O)(=O)N2[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@@H](CC3=CC=CC=C3)C(N[C@H](C(N[C@H](C(O)=O)CS)=O)CC(O)=O)=O)=O)CCCCN)=O)CO)=O)[C@H](CC)C)=O)[C@@H](C)O)=O)CC(N)=O)=O)C)=O)[C@@H](C)O)=O)CCCCN)=O)CCC(O)=O)=O)CCC(O)=O)=O)CCC2

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

168431261