Protease-Activated Receptor-2, amide

SKU: orb1299752

Description

This synthetic hexapeptide amide (SLIGKV-NH2) acts as a potent agonist for Protease-Activated Receptor-2 (PAR2), with a reported half-maximal inhibitory concentration (IC50) of 10.4 µM. It is widely used in vitro and in vivo to study PAR2-mediated signaling in inflammation, pain, and metabolic research.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 190383-13-2
• MW: 614.78
• Purity: >99.99% (May vary between batches)
• Formula: C₂₈H₅₄N₈O₇
• SMILES: CC[C@H](C)[C@H](NC(=O)[C@H](CC(C)C)NC(=O)[C@@H](N)CO)C(=O)NCC(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)C)C(N)=O
• Target: Protease-activated Receptor
• Solubility: H2O:33.33 mg/mL (54.21 mM)

Bioactivity

• Target IC50:
  PAR2:10.4 M

Storage & Handling

• Storage: keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

PAR2, inhibit, Inhibitor, Proteaseactivated Receptor, ProteaseactivatedReceptor, ProteaseActivated Receptor2, amide, Protease-Activated Receptor-2, Amide, Protease-Activated Receptor (PAR), Protease Activated Receptor 2, amide, Protease Activated Receptor (PAR), SLIGKV-NH2, Thrombin receptors

Compound Identifiers

PubChem CID

10483914