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PROTAC TEAD/IAP degrader-1

SKU: orb3210527

Description

PROTAC TEAD/IAP degrader-1 is a TEAD/IAP PROTAC degrader that facilitates the recruitment of cIAP1 to form a ternary complex, inducing ubiquitination and proteasomal degradation of TEAD1 and TEAD4. This compound suppresses the transcriptional activity of TEAD, decreases the expression level of CTGF, and inhibits cell proliferation. It is applicable in mesothelioma research.

Images & Validation

Key Properties

TargetIAP,YAP,PROTACs

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information