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PROTAC TEAD1/IAP degrader-3

SKU: orb3210080

Description

PROTAC TEAD1/IAP degrader-3 is a TEAD1/IAP PROTAC degrader that facilitates the formation of a ternary complex by recruiting cIAP1 and XIAP E3 ligase, leading to the proteasomal degradation of TEAD1. It also triggers the autoubiquitination and proteasomal degradation of cIAP1. This compound can inhibit cell proliferation and regulate the Hippo pathway activity by downregulating CTGF gene expression in a TEAD-dependent manner. PROTAC TEAD1/IAP degrader-3 is applicable in mesothelioma research.

Images & Validation

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PROTAC TEAD1/IAP degrader-3

Key Properties

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TargetPROTACs,YAP

Storage & Handling

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Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Quality Guarantee

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Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

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Gene Symbol
PROTACs,YAP

Protocol Information

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