PROTAC SMARCA2 degrader-23

SKU: orb2695224

Description

PROTAC SMARCA2 degrader-23 (Example 1) is a potent and selective degrader of the SMARCA2 protein, demonstrating a DC50 below 100 nM. This compound is a valuable chemical probe for oncology research, enabling the study of SMARCA2 function in both cellular and in vivo cancer models.

Research Area

Epigenetics & Chromatin, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2892523-67-8
• MW: 876.08
• Formula: C₄₇H₅₇N₉O₆S
• SMILES: OC1=C(C=2C=C3C4(CNC3=NN2)CCN(CC4)C5CN(CCOC=6C=C([C@H](C(=O)N7[C@H](C(N[C@@H](C)C8=CC=C(C=C8)C=9SC=NC9C)=O)C[C@@H](O)C7)C(C)C)ON6)CC5)C=CC=C1
• Target: PROTACs,Epigenetic Reader Domain

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

166478081