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PROTAC SKP2 Degrader-1

SKU: orb3210117

Description

PROTAC SKP2 Degrader-1 is a PROTAC degrader targeting SKP2 with a dissociation constant (Kd) of 6.28 μM. It facilitates the targeted degradation of SKP2 via the ubiquitin-proteasome system. This compound stabilizes SOCS1 expression and modulates the expression of the immunoproteasome through the JAK/STAT pathway, thereby inhibiting tumor cell proliferation. PROTAC SKP2 Degrader-1 is applicable in cancer-related research.

Images & Validation

Key Properties

TargetDNA/RNA Synthesis,PROTACs,JAK,Apoptosis,E1/E2/E3 Enzyme,STAT

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
Quality Guarantee

Quality Guarantee

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Protocol Information