PROTAC ROR1 degrader-1

SKU: orb2945034

Description

PROTACROR1degrader-1 (Compound 11d) is a bifunctional PROTAC molecule that selectively targets and degrades the pseudokinase ROR1 with a DC50 of 40-80 nM in NSCLC cells. It induces apoptosis and PARP cleavage in NCI-H23 cells, making it a valuable chemical tool for studying ROR1 biology and targeted protein degradation in cancer research.

Research Area

Cell Biology, Metabolism Research, Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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MW	1081.22
Formula	C₅₅H₇₄BrN₁₁O₅S
Target	Apoptosis,PROTACs,ROR

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Gene Symbol

Apoptosis,PROTACs,ROR

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