PROTAC RAR Degrader-1

SKU: orb1987785

Description

PROTAC RAR Degrader-1 is a heterobifunctional degrader that recruits cIAP1 to target the retinoic acid receptor (RAR) for proteasomal degradation. As a SNIPER, it induces maximal RAR degradation at 30 µM in HT1080 cells and serves as a tool for studying RAR function in cancer and differentiation research.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1351169-27-1
• MW: 917.14
• Formula: C₅₁H₇₂N₄O₁₁
• SMILES: O(CCCNC(COCCOCCOCCNC([C@@H](NC([C@H]([C@@H](CC1=CC=CC=C1)N)O)=O)CC(C)C)=O)=O)C2=C(C(O)=O)C=CC(/C=C/C(=O)C3=CC(C(C)(C)C)=CC(C(C)(C)C)=C3)=C2
• Target: SNIPERs,PROTACs,Retinoid Receptor

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

54764325