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PROTAC PLK1 Degrader-2

SKU: orb3177252

Description

PROTACPLK1 Degrader-2 (Compound NC1) is a PLK1 PROTAC degrader with a dissociation constant (Kd) of 6.06 μM. It significantly inhibits the proliferation of HeLa cells, inducing cell cycle arrest and apoptosis. In mouse models with HeLa cell xenografts, PROTACPLK1 Degrader-2 displays strong antitumor activity, making it a valuable tool for studying cervical cancer.

Research Area

Cell Biology, Pharmacology & Drug Discovery

Images & Validation

Key Properties

TargetPLK,Apoptosis,PROTACs

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information