PROTAC PARP1 degrader-3

SKU: orb2814257

Description

PROTAC PARP1 degrader-3 (C6) is a potent and selective degrader of PARP1 (DC50 = 58.14 nM). It demonstrates cytotoxic activity in colon cancer cell lines like SW-620 and LOVO and shows synergistic effects with SN-38 in BRCA-mutated models, supporting its use in targeted protein degradation and combination therapy research.

Research Area

Cell Biology, Epigenetics & Chromatin, Molecular Biology, Pharmacology & Drug Discovery

Key Properties

• MW: 896.13
• Formula: C₅₂H₆₅N₉O₅
• Target: PARP,PROTACs

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

PARP,PROTACs