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PROTAC PARP1 degrader-3

SKU: orb2814257

Description

PROTAC PARP1 degrader-3 (C6) is a potent and selective degrader of PARP1 (DC50 = 58.14 nM). It demonstrates cytotoxic activity in colon cancer cell lines like SW-620 and LOVO and shows synergistic effects with SN-38 in BRCA-mutated models, supporting its use in targeted protein degradation and combination therapy research.

Research Area

Epigenetics & Chromatin, Molecular Biology, Pharmacology & Drug Discovery

Images & Validation

Key Properties

MW896.13
FormulaC52H65N9O5
TargetPROTACs,PARP

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

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Protocol Information

PROTAC PARP1 degrader-3 (orb2814257)

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