PROTAC MAGL degrader-1

SKU: orb3028382

Description

PROTACMAGLdegrader-1 is an orally active PROTAC agent that simultaneously targets both monoacylglycerol lipase (MAGL) and the E3 ubiquitin ligase MDM2. It functions by degrading MAGL and inhibiting the interaction between MDM2 and p53. Additionally, PROTACMAGLdegrader-1 has partial blood-brain barrier (BBB) penetration and can induce apoptosis in glioblastoma stem cells (GSC).

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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Target	PROTACs,Ligands for E3 Ligase,MAGL

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Gene Symbol

PROTACs,Ligands for E3 Ligase,MAGL

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