PROTAC K-Ras Degrader-3

SKU: orb2665122

Description

PROTAC K-Ras Degrader-3 is a PROTAC degrader targeting K-Ras, exhibiting a DC50 value of ≤ 1 nM against SW620 KRAS G12D and a GI50 value of ≤ 10 nM in inhibiting the growth of SW620 3D cells. It is used in cancer research.

Key Properties

• CAS Number: 3043670-68-1
• MW: 1012.20
• Formula: C₅₇H₆₇F₂N₉O₆
• SMILES: C(N1CC2(C1)CCN(CC2)C=3C=C4C(=CC3)C(=O)N(C4)[C@@H]5C(=O)NC(=O)CC5)C6(C)CCN(CC7(COC=8N=C(C9=C(N8)C(F)=C(N=C9)C=%10C%11=C(C=C(O)C%10)C=CC(F)=C%11CC)N%12C[C@](C)(O)CCC%12)CC7)CC6
• Target: Ras

Storage & Handling

• Storage: -20°C
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Ras