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PROTAC HSP70 Degrader-1

SKU: orb3210492

Description

PROTAC HSP70 Degrader-1 (compound C4) is an intracellular HSP70 and CRBN ligand that forms a ternary complex by binding to CRBN. This compound facilitates the ubiquitination and proteasomal degradation of cytoplasmic HSP70. It exhibits cytotoxic activity against cancer cells, inhibiting tumor cell proliferation and inducing apoptosis when used in combination with DTHIB. PROTAC HSP70 Degrader-1 is applicable in research on colon cancer and leukemia.

Images & Validation

Key Properties

TargetHSP

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information