PROTAC HDAC4 Degrader-1

SKU: orb3177239

Description

PROTACHDAC4 Degrader-1 (compound SCT-1) is a potent and selective PROTACHDAC4 degrader. It effectively reduces HDAC4 protein levels, induces S phase cell cycle arrest, and inhibits colony formation, leading to the suppression of tumor cell proliferation. The compound has demonstrated inhibitory activity in the H460 mouse model and is applicable in cancer research, including studies of lung cancer.

Research Area

Epigenetics & Chromatin, Molecular Biology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 3036245-14-1
• MW: 886.93
• Formula: C₄₆H₄₉F₃N₆O₉
• SMILES: O=C1C2=CC=C(C=C2C(=O)N1C3C(=O)NC(=O)CC3)N4CCN(C(=O)CCCCCCCCOC5=C(C(=O)N(C6=CC=C(C=C6)C(F)(F)F)C)C(=O)N(C=7C=CC=C(OC)C57)C)CC4
• Target: PROTACs,HDAC

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

PROTACs,HDAC