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PROTAC FLT3/GSPT1/IKZF1/3 degrader-1

SKU: orb3135999

Description

PROTACFLT3/GSPT1/IKZF1/3 degrader-1 is an FLT3 PROTAC degrader with DC50 = 1.2 nM. It functions as a molecular glue to degrade its brain substrates and exhibits antiproliferative activity against resistant acute myeloid leukemia (AML) cells, showing potential applications in AML research.

Research Area

Cardiovascular Research, Epigenetics & Chromatin; Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

Key Properties

TargetFLT,IKZF,PROTACs,Molecular Glues

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information