PROTAC erf3a Degrader-2

SKU: orb2664210

Description

PROTACerf3a Degrader-2 (C59) is an orally bioavailable small molecule that degrades eRF3a (GSPT1) and downregulates SRD5A3, inhibiting cancer cell proliferation. It is used in vitro and in vivo research for studying prostate, ovarian, liver, cervical, leukemia, and breast cancers.

Key Properties

• CAS Number: 3033871-15-4
• MW: 760.92
• Formula: C₄₄H₅₂N₆O₆
• SMILES: C[C@@]12[C@]([C@]3([C@@]([C@]4(C)[C@@](CC3)(NC(=O)C=C4)[H])(CC1)[H])[H])(CC[C@@H]2C(NC5=CC(N[C@H]6C[C@H](NC7=C8C(C(=O)N(C8=O)C9C(=O)NC(=O)CC9)=CC=C7)CCC6)=CC=C5)=O)[H]

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

172638539