PROTAC CDK4/6/9 degrader 1

SKU: orb3175299

Description

PROTACCDK4/6/9 degrader 1 is a PROTAC degrader targeting CDK4/6/9. It effectively degrades CDK4, CDK6, and CDK9 within triple-negative breast cancer (TNBC) cells, thereby inhibiting their proliferation. Additionally, PROTACCDK4/6/9 degrader 1 induces G1 phase arrest, promotes apoptosis, and suppresses cell migration and invasion in TNBC cells. This compound is useful for researching triple-negative breast cancer (TNBC).

Key Properties

• CAS Number: 3064994-97-1
• MW: 955.13
• Formula: C₅₁H₆₂N₁₂O₇
• SMILES: O=C1C2=CC=C(C=C2C(=O)N1C3C(=O)NC(=O)CC3)N4CCN(C(=O)CN5CCC(CN6CCN(CC(=O)C7=CC=C(C=C7)NC=8N=CC=9C=C(C(=O)N(C)C)N(C9N8)C%10CCCC%10)CC6)CC5)CC4
• Target: Apoptosis,CDK,PROTACs

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Apoptosis,CDK,PROTACs