PROTAC BTK Degrader-13

SKU: orb2945030

Description

PROTAC BTK Degrader-13 is a bifunctional degrader that potently depletes BTK (DC50=0.27 µM) and inhibits its kinase activity (IC50=0.44 µM). It also suppresses ITK and p38 MAPK, blocking BCR signaling, making it a useful chemical probe for studying B-cell malignancies and autoimmune disorders in vitro.

Research Area

Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction

Images & Validation

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Key Properties

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MW	622.63
Formula	C₃₃H₃₀N₆O₇
Target	p38 MAPK,BTK,PROTACs,Tyrosine Kinases

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Gene Symbol

p38 MAPK,BTK,PROTACs,Tyrosine Kinases

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