PROTAC BRD4 Degrader-5-CO-PEG3-N3

SKU: orb2663901

Description

PROTAC BRD4 Degrader-5-CO-PEG3-N3 is a clickable reagent featuring the BRD4-targeting molecule GNE-987 conjugated to an azide-terminated PEG linker. It enables modular PROTAC assembly via CuAAC or SPAAC click chemistry, facilitating targeted protein degradation studies in chemical biology and drug discovery research both in vitro and in cellular models.

Research Area

Epigenetics & Chromatin, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2704602-92-4
• MW: 1231.87
• Purity: 99.17%
• Formula: C₅₈H₇₅ClN₁₂O₁₂S₂
• SMILES: CC=1C2=C(N3C([C@H](CC(NCCOCCOCCOCC(N[C@H](C(=O)N4[C@H](C(N[C@@H](C)C5=CC=C(C=C5)C6=C(C)N=CS6)=O)C[C@@H](OC(COCCOCCOCCN=[N+]=[N-])=O)C4)[C@@](C)(C)C)=O)=O)N=C2C7=CC=C(Cl)C=C7)=NN=C3C)SC1C
• Target: PROTACs,Epigenetic Reader Domain

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

146673077