PROTAC BRD4 Degrader-27

SKU: orb2663678

Description

PROTAC BRD4 Degrader-27 is a heterobifunctional degrader that selectively targets BRD4 over BRD2/3. It is constructed from a pomalidomide-derived E3 ligase ligand, a γ-aminobutyric acid linker, and a BRD4-targeting warhead. This compound is a research tool for investigating BRD4 biology and targeted protein degradation in cellular models.

Research Area

Epigenetics & Chromatin, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2407163-44-2
• MW: 708.67
• Formula: C₃₇H₃₀F₂N₆O₇
• SMILES: O=C1NC(=O)C(N2C(=O)C=3C=CC=C(NCCCC(=O)NC=4C=CC(OC5=CC=C(F)C=C5F)=C(C4)C6=CN(C(=O)C=7NC=CC67)C)C3C2=O)CC1
• Target: Epigenetic Reader Domain|||PROTACs

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

146293986