PROTAC Bcl-xL degrader-1

SKU: orb1983327

Description

PROTAC Bcl-xL degrader-1 is a heterobifunctional molecule that potently degrades Bcl-xL via IAP E3 ligase recruitment. It demonstrates cytotoxic activity in vitro, with IC50 values of 62 nM in human platelets and 8.5 µM in MyLa 1929 cells, supporting its use in apoptosis and oncology research.

Research Area

Cell Biology, Pharmacology & Drug Discovery

Images & Validation

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Key Properties

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MW	1514.28
Formula	C₇₆H₉₆ClF₃N₁₀O₁₁S₃
Target	Bcl-2 Family,Others,PROTACs

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Gene Symbol

Bcl-2 Family,Others,PROTACs

Protocol Information

Find More Protocols

CAS Number:	3034204-25-3
MW:	558.69
Formula:	C₂₈H₃₈N₄O₆S

CAS Number:	3034202-16-6
MW:	1101.75
Formula:	C₅₃H₆₄ClF₃N₆O₈S₃

CAS Number:	2450350-91-9
MW:	658.78
Formula:	C₃₄H₅₀N₄O₉

PROTAC Bcl-xL degrader-1

Description

Research Area

Images & Validation

Key Properties

Storage & Handling

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