Propylbenzilylcholine mustard

SKU: orb3210541

Description

Propylbenzilylcholine mustard (PrBCM) is an irreversible, covalently binding selective antagonist for muscarinic receptors in rat hearts, specifically targeting receptor subtypes with low agonist affinity. This compound can inactivate these receptors in vitro in a dose- and time-dependent manner, maintaining receptor selectivity across various ionic strengths and GTP-containing buffers. PrBCM is utilized in fundamental pharmacological studies of muscarinic receptor structure and function, with a focus on cardiac muscarinic receptor heterogeneity and cardiovascular pharmacology research.

Key Properties

• CAS Number: 36167-80-3
• MW: 375.89
• Formula: C₂₁H₂₆ClNO₃
• SMILES: O=C(OCCN(CCCl)CCC)C(O)(C=1C=CC=CC1)C=2C=CC=CC2
• Target: AChR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

AChR