Propidium Iodide

SKU: orb1306410

Description

Propidium iodide (PI) is a red-fluorescent nucleic acid stain used for identifying dead cells in assays like flow cytometry and microscopy. Its fluorescence intensifies upon DNA/RNA binding, shifting its Ex/Em peaks, making it vital for viability studies in both in vitro and in vivo research contexts.

Research Area

Cell Biology

Key Properties

• Target: Substrate / Probe
• Molecular Weight: 668.4
• Purity: >95%
• CAS Number: 25535-16-4
• Formula: C₂₇H₃₄I₂N₄
• SMILES: [I-].[I-].CC[N+](C)(CC)CCC[n+]1c(-c2ccccc2)c2cc(N)ccc2c2ccc(N)cc12

Storage & Handling

• Storage: -20°C
• Form/Appearance: powder
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, Inhibitor, Propidium, Propidium Iodide, PI

Compound Identifiers

PubChem CID

104981

Yuan Wang, Fuquan Chen, Zhe Yang, Man Zhao, Shuqin Zhang, Yuen Gao, Jinyan Feng, Guang Yang, Weiying Zhang, Lihong Ye, Xiaodong Zhang The Fragment HMGA2-sh-3p20 from HMGA2 mRNA 3′UTR Promotes the Growth of Hepatoma Cells by Upregulating HMGA2 Scientific Reports, 7, 1 (2017)

PubMed: 28522832

Applications

FC

Seyedehreyhaneh Seyedshirazi et al. Infection control and anti-apoptotic effect of Lactobacillus paracasei derivatives on fibroblasts through modulation of BCL2 transcription Arch Microbiol, (2026)

PubMed: 42440161