Procyanidin B2-3'-O-gallate

SKU: orb3179524

Description

Procyanidin B2-3'-O-gallate is a mono-gallate ester isolated from grape seed extract. This compound exhibits anticancer properties, specifically reducing the viability of prostate cancer cells (LNCaP). Additionally, Procyanidin B2-3'-O-gallate can induce apoptosis by cleaving caspases-9 and -3 as well as PARP, while downregulating the levels of Bcl-2, Bcl-Xl, and the androgen receptor.

Research Area

Cell Biology, Epigenetics & Chromatin, Metabolism Research, Molecular Biology, Protein Biochemistry

Images & Validation

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Key Properties

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CAS Number	109280-47-9
MW	730.63
Formula	C₃₇H₃₀O₁₆
SMILES	O(C(=O)C1=CC(O)=C(O)C(O)=C1)[C@@H]2[C@H](C=3C(O[C@@H]2C4=CC(O)=C(O)C=C4)=CC(O)=CC3O)C5=C6C(C[C@@H](O)[C@H](O6)C7=CC(O)=C(O)C=C7)=C(O)C=C5O
Target	Androgen Receptor,Apoptosis,Caspase,Bcl-2 Family,PARP

Storage & Handling

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Storage	-20°C
Expiration Date	12 months from date of receipt.
Disclaimer	For research use only

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Quick Database Links

Gene Symbol

Androgen Receptor,Apoptosis,Caspase,Bcl-2 Family,PARP

Protocol Information

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