PRMT7-IN-2

SKU: orb3135106

Description

PRMT7-IN-2 (A33) is a selective inhibitor of PRMT7 with an IC50 value of 0.50 μM. It causes cell cycle arrest at the G0/G1 phase, induces apoptosis, and inhibits cell growth both in vivo and in vitro. PRMT7-IN-2 reduces monomethylation levels of arginine by PRMT7, increases the expression of the epithelial marker E-cadherin, and decreases the expression of mesenchymal markers N-cadherin, Vimentin, and ZEB2.

Research Area

Cell Biology, Epigenetics & Chromatin

Key Properties

• CAS Number: 3058094-83-7
• MW: 473.55
• Formula: C₂₅H₂₃N₅O₃S
• SMILES: N1=C(N=C(NC=2C=CC=3N=C(C=C(N)C3C2)C)C=4SC=CC14)C5=CC(OC)=C(OC)C(OC)=C5
• Target: Histone Methyltransferase,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Histone Methyltransferase,Apoptosis