PRMT5-IN-32

SKU: orb2565440

Description

PRMT5-IN-32 is a potent and selective PRMT5 inhibitor, demonstrating anti-proliferative activity in HCT116 colorectal cancer cells with an IC50 of 0.13 µM. This compound is a valuable chemical probe for investigating PRMT5 biology in cancer research and epigenetic studies, both in vitro and in vivo.

Research Area

Epigenetics & Chromatin

Key Properties

• CAS Number: 2918815-34-4
• MW: 523.48
• Formula: C₂₇H₂₁F₄N₅O₂
• SMILES: C(N1[C@@]2(C=3C(C1=O)=CC(F)=CC3)C(=O)N(CC4=C(F)C=C(F)C(F)=C4)CC2)C5=CC=6C(N5)=NC(N)=CC6C
• Target: Histone Methyltransferase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

167507134