PRMT5-IN-29

SKU: orb2278819

Description

PRMT5-IN-29 is a potent and orally bioavailable PRMT5 inhibitor with an IC50 of 1.5 µM. This compound is a valuable chemical probe for investigating PRMT5 biology in cancer research, supporting both in vitro enzymatic assays and in vivo efficacy studies in preclinical models.

Research Area

Epigenetics & Chromatin

Key Properties

• CAS Number: 2242788-69-6
• MW: 492.74
• Formula: C₁₈H₂₀Cl₃N₅O₅
• SMILES: O[C@H]1[C@H](N2C3=C(N=C2)\C(=N\OC)\N=CN3)O[C@]([C@](C)(O)C4=CC(Cl)=C(Cl)C=C4)([C@H]1O)[H].Cl
• Target: Histone Methyltransferase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

155169689