Pristimerin

SKU: orb1302332

Description

Pristimerin is a natural triterpenoid with demonstrated anticancer and anti-inflammatory properties. Research indicates it suppresses hypoxia-induced metastasis by reversing stemness and EMT in cancer cells, and inhibits arthritis progression by blocking the ROS/IKK/NF-κB pathway to reduce inflammation and joint damage in vivo.

Research Area

Infectious Disease & Virology, Signal Transduction

Key Properties

• CAS Number: 1258-84-0
• MW: 464.64
• Purity: 99.59% (May vary between batches)
• Formula: C₃₀H₄₀O₄
• SMILES: COC(=O)[C@@]1(C)CC[C@]2(C)CC[C@]3(C)C4=CC=C5C(C)=C(O)C(=O)C=C5[C@]4(C)CC[C@@]3(C)[C@@H]2C1
• Target: NF-κB|||Antibacterial
• Solubility: DMSO:11.82 mg/mL (25.44 mM)

Bioactivity

• Target IC50:
  MGL:93 nM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Inhibitor, inhibit, NF-κB, NFκB, NFkB, NF-kB, Celastrol methyl ester, Bacterial, Pristimerin

Compound Identifiers

PubChem CID

86280086