Prim-O-glucosylcimifugin

SKU: orb1303725

Description

Prim-O-glucosylcimifugin is a small molecule that suppresses TNF-α-induced smooth muscle cell proliferation by inducing cell cycle arrest at the G0/G1 phase. This activity makes it a candidate for research in vascular pathologies, such as atherosclerosis and restenosis, in both cellular and animal models.

Research Area

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Neuroscience, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 80681-45-4
• MW: 468.45
• Purity: 99.54% (May vary between batches)
• Formula: C₂₂H₂₈O₁₁
• SMILES: COc1c2C[C@H](Oc2cc2oc(CO[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)cc(=O)c12)C(C)(C)O
• Target: COX|||JAK|||NO Synthase|||TNF
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.27 mM);DMSO:125 mg/mL (266.84 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

COX, Cyclooxygenase, Cimifugin 7-glucoside, Cimifugin b-D-glucopyranoside, Cimifugin beta-D-glucopyranoside, Cimifugin β-D-glucopyranoside, Inhibitor, inhibit, NOSynthase, NOS, Nitric oxide synthases, NO Synthase, Prim O glucosylcimifugin, PrimOglucosylcimifugin, Prim-O-glucosylcimifugin, TNF-α

Compound Identifiers

PubChem CID

14034912