PRGL493

SKU: orb1694420

Description

PRGL493 is a potent inhibitor of ACSL4, blocking arachidonoyl-CoA synthesis. It suppresses proliferation and migration in PC3 and MDA-MB-231 cells in vitro and inhibits tumor growth in a PC3 mouse xenograft model in vivo. This compound is a valuable tool for researching lipid metabolism in cancer biology and oncology.

Research Area

Cell Biology

Key Properties

• CAS Number: 2479378-45-3
• MW: 451.48
• Purity: 99.11% (May vary between batches)
• Formula: C₂₅H₂₁N₇O₂
• SMILES: CC(=O)NC1=NC(N2C(Nc3ccccc23)=N1)c1cn(nc1-c1ccc(C)o1)-c1ccccc1
• Target: Others
• Solubility: Chloroform:1 mg/mL (2.21 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.21 mM);DMSO:3.66 mg/mL (8.11 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

PRGL 493, PRGL493, PRGL-493, long-chain acyl-CoA synthetase 4

Compound Identifiers

PubChem CID

154685871