Prexasertib mesylate

SKU: orb1690002

Description

Prexasertib (LY2606368) is a potent, selective inhibitor of checkpoint kinases CHK1 and CHK2. It induces replication catastrophe and DNA damage in S-phase cells, enhancing the efficacy of conventional therapies in models of acute lymphoblastic leukemia, as demonstrated in both in vitro and in vivo research.

Research Area

Cell Biology, Molecular Biology

Key Properties

• CAS Number: 1234015-55-4
• MW: 461.49
• Formula: C₁₉H₂₃N₇O₅S
• SMILES: N#CC1=NC=C(N=C1)NC2=NNC(=C2)C=3C(OC)=CC=CC3OCCCN.O=S(=O)(O)C
• Target: DNA/RNA Synthesis,Others,Chk,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

46837045