Prexasertib lactate

SKU: orb2564329

Description

Prexasertib lactate is a potent, ATP-competitive CHK1 inhibitor (Ki=0.9 nM) with additional activity against CHK2 and RSK1. It induces DNA damage and apoptosis, demonstrating antitumor efficacy in both cellular assays and in vivo xenograft models across various cancer research fields.

Research Area

Cell Biology, Molecular Biology

Key Properties

• CAS Number: 2781996-46-9
• MW: 455.47
• Formula: C₂₁H₂₅N₇O₅
• SMILES: [C@@H](C(O)=O)(C)O.O(CCCN)C1=C(C(OC)=CC=C1)C2=CC(NC=3C=NC(C#N)=CN3)=NN2
• Target: DNA/RNA Synthesis,Chk,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

165412107