Praziquantel

• Catalog Number: orb1308625
• Category: Small Molecules
• Description: Praziquantel
• CAS Number: 55268-74-1
• Purity: 99.86%
• MW: 312.41
• SMILES: O=C(C1CCCCC1)N1CC2N(CCC3=C2C=CC=C3)C(=O)C1
• Formula: C₁₉H₂₄N₂O₂
• Biological Activity: Praziquantel (Droncit) increases the permeability of the tegument of susceptible worms, resulting in an influx and increase in intra-tegumental calcium leading to rapid contractions and paralysis of the worm's musculature through a subsequent increase in levels of calcium in the sarcoplasmic reticulum. Praziquantel is a pyrazinoisoquinoline derivative with anthelminthic property. In addition, vacuolization of the tegumental syncytium and blebbing results in tegument disintegration, leads to antigen exposure and elicit host defense responses to the worm.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.