Pralsetinib HCl (2097132-94-8 free base)

SKU: orb1983618

Description

Pralsetinib is a potent and selective next-generation RET inhibitor effective against wild-type RET, key mutants (V804L, V804M, M918T), and CCDC6-RET fusions. Similarly, BLU-667 (pralsetinib) is a highly selective RET inhibitor targeting oncogenic fusions, mutations, and anticipated resistance variants. This small molecule is a valuable tool for in vitro biochemical assays and in vivo cancer model research targeting RET-driven pathologies.

Key Properties

• MW: 570.07
• Formula: C₂₇H₃₃ClFN₉O₂
• SMILES: O=C([C@@]1(OC)CC[C@@H](C2=NC(NC3=NNC(C)=C3)=CC(C)=N2)CC1)N[C@H](C4=CC=C(N5N=CC(F)=C5)N=C4)C.[H]Cl
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

146015303