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Catalog Number | orb1307857 |
---|---|
Category | Small Molecules |
Description | PQR530 |
CAS Number | 1927857-61-1 |
Purity | 99.78% |
MW | 407.42 |
SMILES | C(F)(F)C=1C(=CN=C(N)C1)C=2N=C(N=C(N2)N3CCOCC3)N4[C@@H](C)COCC4 |
Formula | C18H23F2N7O2 |
Biological Activity | PQR530 is a highly potent dual pan-PI3K/mTORC1/2 inhibitor. PQR530 inhibited protein kinase B (PKB, pSer473) and ribosomal protein S6 (pS6, pSer235/236) phosphorylation with IC50 values of 0.07 μM. It also showing antitumor activity. |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |
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