PPARγ phosphorylation inhibitor 1

SKU: orb1687490

Description

PPARγ phosphorylation inhibitor 1 (Compound 10) is a high-affinity PPARγ ligand that potently blocks CDK5-mediated phosphorylation at Ser273 with minimal classical agonism. This mechanism makes it a valuable research tool for studying insulin sensitization in type 2 diabetes, applicable in both cellular assays and animal models of metabolic disease.

Research Area

Metabolism Research, Molecular Biology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2882975-84-8
• MW: 441.26
• Purity: 99.86% (May vary between batches)
• Formula: C₂₂H₁₄Cl₂N₂O₄
• SMILES: O=C(O)C1=NN(C(=O)C=2C=C(OC=3C=CC=CC3)C=CC12)CC4=CC=C(Cl)C(Cl)=C4
• Target: PPAR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

PPAR