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PPARγ modulator-2

SKU: orb2945026

Description

PPARγ modulator-2 (Compound (R)-2n) is a potent and reversible inhibitor of the PPARγ ligand-binding domain (IC50 = 41 nM). This small molecule demonstrates antidiabetic effects in vitro and in vivo, including improved glucose tolerance and insulin sensitivity in db/db mouse models, supporting metabolic disease research.

Research Area

Metabolism Research, Molecular Biology

Images & Validation

Key Properties

CAS Number2897652-01-4
MW634.6
FormulaC26H21NO7S3Se
SMILESO=S(=O)(OC=1C=CC(=CC1)S2(=O)=N[Se]C=3C=C(OS(=O)(=O)C4=CC=C(C=C4)C)C=CC32)C5=CC=C(C=C5)C
TargetPPAR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

Protocol Information