PPARγ-IN-2

SKU: orb1944193

Description

PPARγ-IN-2 (Compound 5a) is a potent PPARγ inhibitor with an EC50 of 0.106 μM against triglyceride accumulation in 3T3-L1 adipocytes. In vivo, it mitigates high-fat diet-induced obesity and metabolic syndrome, reducing adipose tissue lipid content, making it a valuable tool for metabolic disease research.

Research Area

Metabolism Research, Molecular Biology

Key Properties

• CAS Number: 2682078-97-1
• MW: 335.4
• Formula: C₁₉H₂₁N₅O
• SMILES: C(=O)C1=C(NC=2C1=CC=CC2)C=3N=C(NCCN4CCCC4)C=CN3
• Target: PPAR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

168510610