PP487

SKU: orb2565446

Description

PP487 is a potent dual tyrosine kinase and PI3K inhibitor, with low nanomolar IC50 values against key targets including DNA-PK, mTOR, Src, and PDGFR. This small molecule is a valuable research tool for investigating oncogenic signaling pathways in both in vitro and in vivo cancer studies.

Research Area

Cardiovascular Research, Molecular Biology, Signal Transduction

Key Properties

• CAS Number: 1092787-12-6
• MW: 348.2
• Formula: C₁₄H₁₄BrN₅O
• SMILES: NC1=C2C(=NN(C(C)C)C2=NC=N1)C3=CC(O)=C(Br)C=C3
• Target: Src,Bcr-Abl,mTOR,c-Met/HGFR,DNA-PK,PI3K,EGFR,VEGFR,PDGFR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

24905145