Posaconazole hydrate

SKU: orb1704215

Description

Posaconazole is a potent second-generation triazole antifungal that acts by inhibiting the cytochrome P450 enzyme sterol 14α-demethylase (IC50: 0.25 nM). It is widely used in research for studying invasive fungal infections, with applications in both in vitro susceptibility assays and in vivo animal models of aspergillosis and candidiasis.

Research Area

Infectious Disease & Virology

Key Properties

• CAS Number: 1198769-38-8
• MW: 718.79
• Formula: C₃₇H₄₄F₂N₈O₅
• SMILES: C([C@@]1(C[C@H](COC2=CC=C(C=C2)N3CCN(CC3)C4=CC=C(C=C4)N5C(=O)N([C@H]([C@H](C)O)CC)N=C5)CO1)C6=C(F)C=C(F)C=C6)N7C=NC=N7.O
• Target: Antifungal,Parasite,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

78357825