Porfiromycin

SKU: orb1740805

Description

Porfiromycin, an N-methyl derivative of mitomycin C, is a bioreductive antibiotic that alkylates DNA and generates oxygen radicals, causing interstrand cross-links and single-strand breaks to inhibit DNA synthesis. Its selective toxicity toward hypoxic cells makes it a valuable tool for researching tumor hypoxia, DNA damage mechanisms, and combination therapies in both in vitro and in vivo cancer models.

Research Area

Molecular Biology

Key Properties

• CAS Number: 801-52-5
• MW: 348.35
• Formula: C₁₆H₂₀N₄O₅
• SMILES: O(C)[C@]12N(C3=C([C@H]1COC(N)=O)C(=O)C(N)=C(C)C3=O)C[C@]4([C@@]2(N4C)[H])[H]
• Target: DNA Alkylator/Crosslinker,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

13116