Pomalidomide-PEG1-C2-N3

SKU: orb1988392

Description

Pomalidomide-PEG1-C2-N3 is a cereblon ligand-linker conjugate used in PROTAC design, such as the CDK6 degrader CP-10. This compound enables targeted protein degradation research, with applications in studying CDK6's role in cancer biology in vitro, as demonstrated by CP-10's potent DC50 of 2.1 nM.

Research Area

Pharmacology & Drug Discovery, Pharmacology & Drug Discovery; Cell Biology

Key Properties

• CAS Number: 2271036-44-1
• MW: 386.36
• Formula: C₁₇H₁₈N₆O₅
• SMILES: [N-]=[N+]=NCCOCCNC1=CC=CC=2C(=O)N(C(=O)C12)C3C(=O)NC(=O)CC3
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

138857982