Pomalidomide-NH-PEG6-amide-C2-CPI-1612

SKU: orb3133519

Description

Pomalidomide-NH-PEG6-amide-C2-CPI-1612 (compound 22 (dCE-1)) is a CBP/EP300 degrader. It consists of the CRBN ligand Pomalidomide, a 24-atom chain with 6 PEG units, and the HAT inhibitor CPI-1612. This compound exhibits antiproliferative effects on multiple myeloma cells LP1 (DC50 = 1.2 μM), MM1S, and various cancer cells, notably leukemia cells.

Research Area

Pharmacology & Drug Discovery

Key Properties

• Formula: C₅₇H₆₈N₁₀O₁₂
• Target: PROTACs

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

PROTACs