Polmacoxib

• Catalog Number: orb1306413
• Category: Small Molecules
• Description: Polmacoxib
• CAS Number: 301692-76-2
• Purity: 98.49%
• MW: 361.39
• SMILES: O=C1C(=C(OC1(C)C)C2=CC=C(S(N)(=O)=O)C=C2)C3=CC(F)=CC=C3
• Formula: C₁₈H₁₆FNO₄S
• Biological Activity: Polmacoxib (CG 100649) is a first-in-class NSAID drug candidate, is a dual inhibitor of carbonic anhydrase (CA) and COX-2. Polmacoxib inhibits premalignant and malignant colorectal lesions in mouse models, partly through inhibiting tumor cell proliferation.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.