POLA1 inhibitor 1

SKU: orb1687863

Description

Compound 12 is an orally bioavailable POLA1 inhibitor with demonstrated antitumor activity in both in vitro and in vivo studies. It shows efficacy against various tumor types and retains potency in Adaroten-resistant cell lines, making it a useful research tool for investigating DNA replication and cancer therapeutics.

Research Area

Cell Biology, Molecular Biology, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 2217671-41-3
• MW: 417.5
• Formula: C₂₆H₂₇NO₄
• SMILES: O\N=C\c1cc(\C=C\C(O)=O)ccc1-c1ccc(O)c(c1)C12CC3CC(CC(C3)C1)C2
• Target: DNA/RNA Synthesis,Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

164517069