Podofilox

SKU: orb1309699

Description

Podofilox, also known as (+)-Shikonin, is a lignan derived from Podophyllum resin. It acts as a potent spindle poison and keratolytic agent, making it a research tool for studying antimitotic mechanisms, wart treatments, and potential antineoplastic applications in both in vitro and in vivo models.

Research Area

Molecular Biology, Signal Transduction

Key Properties

• CAS Number: 518-28-5
• MW: 414.41
• Purity: 99.59%
• Formula: C₂₂H₂₂O₈
• SMILES: O=C1[C@@]2([C@@H](C=3C([C@H](O)[C@]2(CO1)[H])=CC4=C(C3)OCO4)C5=CC(OC)=C(OC)C(OC)=C5)[H]
• Target: Microtubule Associated,Topoisomerase
• Solubility: DMSO:25 mg/mL (60.33 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.41 mM)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

(+)-Shikonin, inhibit, MicrotubuleAssociated, Microtubule/Tubulin, microtubule, Microtubule Associated, Inhibitor, Topo II, Podophyllotoxin, Podofilox, Shikonin

Compound Identifiers

PubChem CID

10607